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FDA Approves Abuse-Resistant Painkiller 2011-06-20
Author: Drug Discovery & Development Staff
From: Drug Discovery & Development
Pfizer Inc. and Acura Pharmaceuticals Inc. said the Food and Drug Administration approved a powerful painkiller that is designed to be harder to abuse. The FDA cleared marketing of Oxecta as an immediate-release treatment for acute or moderate-to-severe pain. The drug also contains niacin, which cau
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Higher-dose antiepileptics increase risk of congenital malformations 2011-06-16
Author: Drug Topics Staff
From: Drug Topics
The risk of major congenital malformations increases dose-dependently with 4 common antiepileptic drugs, according to the results of a study published online June 5 in The Lancet Neurology. However, “the risk of major congenital malformations is influenced not only by type of antiepileptic drug, but
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FDA Adds New Zocor Warnings 2011-06-10
Author: Matthew Perrone
From: Drug Discovery & Development
The Food and Drug Administration has added new warnings to the blockbuster cholesterol drug Zocor, cautioning doctors that the highest dose of the drug can cause muscle damage, including potentially lethal kidney damage in rare cases.
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Pfizer Opens New Center for Therapeutic Innovation 2011-06-09
Author: Linda A. Johnson
From: Drug Discovery & Development
Drugmaker Pfizer Inc. said it is starting a major research collaboration with Boston area scientists, putting them in charge of their own projects to speed up and improve discovery of new medicines.
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Studies find new drugs boost skin cancer survival 2011-06-06
From: Bioscience Technology
Two novel drugs produced unprecedented gains in survival in separate studies of people with melanoma, the deadliest form of skin cancer, doctors reported Sunday. In one study, an experimental drug showed so much benefit so quickly in people with advanced disease that those getting a comparison drug
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Iron May Be Key to Brain-Tumor Drug Delivery 2011-06-02
Author: Bioscience Technology Staff
From: Bioscience Technology
Brain cancer therapy may be more effective if the expression of an iron-storing protein is decreased to enhance the action of therapeutic drugs on brain cancer cells, according to Penn State College of Medicine researchers. Malignant glioblastoma multiforme is a deadly brain tumor for which no long-
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Molecular Mimicry Could Be Key to Drug Resistance 2011-06-02
Author: Drug Discovery & Development Staff
From: Drug Discovery & Development
Using genomic sequencing, the spelling out of billions of genetic instructions stored in DNA, the study identified several methyltransferase protein families that are very similar in otherwise very distantly related human bacterial pathogens. These proteins also were found in hosts such as humans, m
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E. coli Outbreak May Be a New Strain 2011-06-02
Author: Peter Russell
The E. coli outbreak that has left several dead and hundreds ill across Europe -- and may now have caused two U.S. travelers to become ill -- is a new strain that has never been seen before, according to an official at the World Health Organization (WHO).
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Dow Plants Earn IPEA Certification 2011-06-01
Author: Drug Discovery & Development Staff
From: Drug Discovery & Development
The Dow Chemical Company announced that the Plaquemine, Louisiana and Freeport, Texas North American manufacturing operations of its newly branded propylene glycol (PG) USP/EP product – DOW PuraGuard Propylene Glycol USP/EP – has passed key independent quality audits and earned third-party certifica
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Cellphones a 'possible' carcinogen _ like coffee 2011-05-31
From: Bioscience Technology
A respected international panel of scientists says cellphones are possible cancer-causing agents, putting them in the same category as the pesticide DDT, gasoline engine exhaust and coffee.
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