Thermo Fisher Scientific Inc. has introduced the Nunclon Vita stem cell culture surface. The energy-treated polystyrene surface enables direct attachment, colony formation and growth of human embryonic stem cells (ESC) and induced pluripotent stem cells (IPS), without the need for feeder cells or matrix coatings. In media supplemented with a Rho-associated kinase (ROCK) inhibitor, human ESCs can be cultured on the Nunclon Vita Surface for at least 10 passages without any loss of pluripotency, or karyotype changes. As a result, Nunclon Vita represents a significant step forward for stem cell scientists, offering greater control over culturing of stem cells and providing a more stable supply of cells for downstream applications.
By eliminating matrix coatings and feeder cells, the Nunclon Vita surface reduces culture variability and is less labor-intensive than cell lines that require matrix coatings or feeder cells. The Nunclon Vita surface treatment is much more adaptable for scalable cell expansion as cells grow directly on the polystyrene surface. In addition, the new surface works in synergy with a ROCK inhibitor for expansion of human ESC, IPS, as well as human embryonic kidney cells (HEK) to enable enzymatic and mechanical passage protocols.
About this company:
Thermo Fisher Scientific Inc. (NYSE: TMO) is the world leader in serving science, enabling our customers to make the world healthier, cleaner and safer. With annual revenues of $10 billion, we have more than 30,000 employees and serve over 350,000 customers within pharmaceutical and biotech companies, hospitals and clinical diagnostic labs, universities, research institutions and government agencies, as well as environmental and industrial process control settings.
Thermo Fisher Scientific Inc.
81 Wyman Street
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